What type of light therapy does Dermarevolta use?
It involves 311 nm UVB narrowband, monochromatic phototherapy, currently the latest trend and most commonly used light therapy, with a good safety record even among children.A full-sized booth or localized radiation source, such as a UV comb, is used to treat signs that appear on the scalp. UVB radiation at a wavelength of 290-320 nm penetrates into the surface layers of the epidermis or the dermoepidermal junction, intervening in the papillae of the dermis. Basic benefits from radiation include immunosuppression and immunomodulation at the application site, while a side effect is the formation of erythema (redness), which appears for several hours after exposure, reaches the maximum level for 12-24 hours and then subsides after a few days. In later stages, the erythema fades over 2-3 days after administration, creating pigmentation that lasts several days to weeks. UVB radiation also helps create vitamin D precursors in the skin. Additional UV radiation benefits include tanning/burning, thickening of the cornified layer of the skin, peeling of the skin’s top layer and premature skin aging.
What is the regimen for light treatment?
When treatment starts, the patient’s skin phototype, anamnestic tolerance and response to ultraviolet radiation and the instrument’s minimal erythemal dose (MED) are taken into account. 311 nm UVB phototherapy consists of a cycle of 15-25 radiation sessions 2-3 times a week under continuous medical supervision. Radiation doses are tailored to the patient’s requirements and diagnosis, and the length of exposure depends on them. Each radiation session requires a different dosage based on specific tolerance and response to radiation, with exposure prolonged during the cycle, which means the length of a single session gradually increases. Such phototherapy cycles may be administered twice a year, up to the maximum cumulative effective dose.
UVB phototherapy is used either alone or in combination with tar, vitamin D3 analogues, general or local retinoids and UVA. If no complete resorption occurs after 3-6 weeks, “maintenance phototherapy” can continue twice a week for a month and then once a week for another month.
What are the indications for 311 nm UVB phototherapy?
Phototherapy acts locally on the skin as an immunomodulator and immunosuppressor. Due to these effects, phototherapy is used to treat various skin diseases:
What are the contraindications for light therapy?
LTreatment with UVB phototherapy is contraindicated in the presence of any skin cancer - malignant melanoma or non-melanoma skin cancer (basal cell and squamous cell carcinoma), dysplastic naevi syndrome. Light therapy is contraindicated for skin diseases provoked by the sun, so-called “photodermatoses”, when taking photosensitizing medications and medications for polymorphic light eruption. It is inappropriate for people with claustrophobia (311 nm UVB phototherapy is done in a booth) or severe cardiovascular disease (overheating, prolonged standing in the booth). Eyes and some parts of the body need to be protected during radiation (e.g. genitals, pigmented moles covered with paste). A relative contraindication is childhood; children under 3 should not sunbathe or undergo phototherapy.